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Product ID: 12652

Molecular Devices ImageXpress Pico Automated Cell Imaging System

Molecular Devices ImageXpress Pico Automated Cell Imaging System

Includes Computer loaded with Software


The ImageXpress Pico Automated Cell Imaging System is more than a digital microscope, combining high-resolution imaging with powerful analysis. Whether running fluorescence imaging or brightfield assays, the automated imager features comprehensive preconfigured protocols for cell-based assays to shorten the learning curve, so you can start running experiments quickly.



  • Multiple imaging modes: The ImageXpress Pico system offers objectives ranging from 4x to 63x and can operate in colorimetric, brightfield, fluorescence, or Digital Confocal 2D on-the-fly deconvolution imaging modes.
  • Preconfigured analysis protocols:Over 25 preconfigured analysis protocols ranging from simple cell counting to sophisticated neurite tracing analysis. With features like the click-to-find tool, analysis parameters can be optimized by simply clicking on a few cells that match specific criteria.
  • Plate-to-individual cell view:Data can be visualized at multiple levels from plate overview to individual cells. A wide variety of data visualization tools from the plate and cellular level empower users to learn as much as possible from their images and assays.
  • Z-stack acquisition:Generate sharper images for more accurate segmentation using z-stack acquisition. Acquire a series of images at different focal points to capture more detail than with a 
  • Quickly and easily identify regions of interest:Live Preview simplifies identification of regions of interest, letting users pan around the sample and interactively adjust focus with a virtual joystick, saving time and effort.
  • Environmental control:Multi-day, time lapse, and live cell assays can be run using the onboard environmental system with options for humidity, CO2, and O2 control. Optimized to prevent z-drift, the software also provides real-time monitoring of environmental state, ensuring optimal assay conditions.


  • Imaging modes: Transmitted light (brightfield), colorimetric, fluorescence, live-preview
  • Illumination: High power LEDs with >20,000 hour life
  • Objectives: 6 position automated turret with user-exchangeable objectives.
  • HC PL Fluotar 4x/.13 CN: 103157
  • HC PL Fluotar L 20x/.40 CN: 103159
  • HC PL Fluotar 10x/.32 CN: 103201
  • HC PL Fluotar L 40x/.60 CN: 506201
  • HC PL Fluotar L 40x/.60 CORR CN: 506201
  • Camera: Sony CMOS, 5 megapixel
  • Channels: Cy5, TRITC, FITC, DAPI, Texas Red, CFP, white light, and RGB
  • Stage resolution: 0.625 µm
  • Imaging method: Single color, multicolor, time lapse, z-stacking, and Digital Confocal* 2D on-the-fly deconvolution
  • Autofocus method: LED autofocus or image autofocus with LED assist
  • Supported labware: 6- to 384-well plates and 25 mm x 75 mm (1 in. x 3 in.) slides, 35 mm culture dishes
  • Supported operating systems: Windows 10 (main computer), Windows 10 and macOS (clients)
  • Image output: 16-bit TIFF, JPG, MP4
  • Dimensions (in):17.8 (H) x 21.7 (W) x 17.1 (D)
  • Dimensions (cm): 45.3 (H) x 55.1 (W) x 43.5 (D)
  • Weight (kg): 38 kg (84 lb) including options
  • Power: 100 VAC to 240 VAC, 50/60 Hz, 1.6A nominal at 115V, 200 Watts Max
  • Ambient operating temperature: 18°C to 30°C (59°F to 86°F)
  • Temperature control: Ambient +8°C to 40°C
  • Temperature control: homogeneity 37°C ± 0.5°C at 23°C ambient
  • Gas control: O2 control, 1-15% and ambient, CO2 control, ambient to 15%
  • Humidity control: Active humidity control. Sample compartment controlled to 85% relative humidity

Additional Details

  • Manufacturer: Molecular Devices
  • Model Name: ImageXpress Pico Automated
  • Model Number:
  • Product ID: 12652
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